Ultram (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain. Ultram is used to treat moderate to severe pain in adults. The extended-release form of tramadol (Ultram ER) is for around-the-clock treatment of pain. Ultram is a prescription medicine used to treat symptoms of moderate to severe pain. Ultram may be used alone or with other medications. Ultram belongs to a class of drugs called Opioid Analgesics.

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